Diseases of the gastrointestinal tract

Full Name: Grigorios Leontiadis

Academic Affiliation: McMaster University, Department of Medicine, Division of Gastroenterology

Position: Associate Professor

Abstract: Since 2008, the year I moved from the Democritus University of Thrace (Alexandroupolis, Greece) to McMaster University, my research interests include: (1) pharmacological treatment of bleeding from ulcers in the upper gastrointestinal tract, especially with regards to medications that reduce gastric acidity; (2) treatment of Helicobacter pylori infection (one of the main causes of ulcers in the upper gastrointestinal tract); (3) techniques for prevention of complications, especially acute pancreatitis (severe inflammation of the pancreas), following ERCP (an endoscopic therapeutic procedure for diseases of the biliary tract and pancreas); (4) the association between use of proton pump inhibitors (a class of medications that reduce gastric acidity) and a long list of potential adverse effects of these medications (including bone fractures, pneumonia, gastrointestinal infections); (5) methodology for systematic and objective appraisal of the quality of evidence that supports clinical practice guidelines; (6) association between gut microbiome (the bacteria that live in the gastrointestinal tract) and diseases such as inflammatory bowel disease (Crohn’s disease and ulcerative colitis) and irritable bowel syndrome.